出版社:化学工业出版社
年代:2014
定价:150.0
本书共15章,反映了黄皮酰胺研究的热点和最新进展。本书由我国著名药理学家张俊田教授组织编写,国内相关专家对其所擅长的领域编写,各章具有较高学术水平。本书可供从事相关新药研究的科研人员参考阅读。
Recent Advances in the Study of (-)Clausenamide on Chemistry,
Biological Activities and Mechanism of Action1
The Synthesis of Clausenamide Family Natural Products and Analogues14
Pharmacological Activity of Clausenamide as A Chiral Drug33
Neuroprotection of (-)Clausenamide via Inhibiting Tau Hyperphosphorylation
and Preserving Microtubule Structure49
Synaptic Pharmacology of Clausenamide64
Two Forms of Long-term Potentiation Induced by (-)Clausenamide and Rgl73
The Nootropic Mechanism of (-)Clausenamide80
Mechanism of (-)Clausenamide Induced Calcium Transient in Primary Culture
of Rat Cortical Neurons85
(-)Clausenamide Enhances the Synaptic Plasticity through Gasotransmitters96
Antiapoptotic Effect of (-)Clausenamide and its Mechanisms of Action107
The Signal Transduction Pathway of (-)Clausenamide on Activation of
Learning and Memory114
Pharmacokinetics and Metabolism of Clausenamide Enantiomers119
Metabolic Transformation of Clausenamide142
Preclinical Safety Evaluation and General Pharmacology of (-)Clausenamide148
Optical Separation and Quality Research of Clausenamide Enantiomers157
Abstracts in English and Chinese173
张均田教授又一力作《《黄皮酰胺的化学和生物学活性》》,反映了黄皮酰胺的研究水平,是研究人员的重要参考和启发之作。《黄皮酰胺的化学和生物学活性(全英文版)》,本书共15章,反映了黄皮酰胺研究的热点和最新进展。本书由我国著名药理学家张俊田教授组织编写,国内相关专家对其所擅长的领域编写,各章具有较高学术水平。本书可供从事相关新药研究的科研人员参考阅读。